منابع مشابه
THE CYTOCHROME c-AZIDE COMPLEX BY B. L. HORECKER
Since both cyanide and azide have been shown to block the oxidation of cytochrome c by cytochrome oxidase (l), it has been generally accepted that the toxicity of these substances is due to this property. A considerable amount of evidence has accumulated, however, indicating that aside and cyanide do not inhibit respiration in a parallel manner under all conditions. Thus Stannard (2) was able t...
متن کاملThe Cytochrome C-cytochrome Oxidase Complex
In the preceding paper the oxidation of substrates by “indophenol oxidase” was demonstrated to be a joint action of cytochrome and cytochrome oxidase. It was further shown that with a given amount of oxidase the velocity of hydroquinone oxidation reached a maximum as the amount of added cytochrome was increased. The latter fact immediately suggested the probability that the rapid aerobic oxidat...
متن کاملThe cytochrome c-cyanide complex.
In the course of studies involving the reduction of ferricytochrome c by the succinic dehydrogenase system, it was observed that in the presence of cyanide there is a progressive decrease in the amount of reducible eytochrome c. This action of cyanide on cytochrome c had previously been reported by Pott.er (l), together with other evidence indicating the formation of a ferricytochrome c-cyanide...
متن کاملA cytochrome c-phospholipid complex.
Lipids may play an important role in the maintenance of proper spatial configuration between the various members of the mitochondrial electron transport chain (1, 2). Greenlees and Wainio (3) and Hatefi (4) have shown that phospholipids are essential for the activity of cytochrome c oxidase. In its present state of purity, thii enzyme contains approximately 15% phospholipid and may exist as a l...
متن کاملReduction and activity of cytochrome c in the cytochrome c-cytochrome aa3 complex.
Uncharged reductants, such as NNN'N'-tetramethyl-p-phenylenediamine and diaminodurene, reduce cytochrome c at both high and low ionic strength, unlike ascorbate, which is effective only at low ionic strength. The 'tightly bound' cytochrome c-cytochrome c oxidase complex, with 1 equiv. of cytochrome c per cytochrome aa3, can be prepared by simple mixing of the two component species. Its properti...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1948
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)52745-4